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 Geplaatst: 16-08-2018 03:55:38 Onderwerp: The National Institute |
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Fine golden sand and crystal clear water; a perfect picture for a peaceful day Corey Crawford Salute to Service Jersey , full of solitude or romance. For many, combining this is the ultimate in enjoyment. Add water to the mix for those with families, and the peace so hard to come by at home is assured as the children swim in the ocean or build sand castles, leaving parents alone to talk quietly while the children cavort. It's hard to find this tranquil atmosphere at a beach, there are simply too many. The developed, commercialized beaches tend to lose their charm, so to beaches with a towel spread and an umbrella pitched at every few steps.
This is exactly what makes beaches in Asia more desirable than the overcrowded resort paradises advertised so heavily. The potential to stroll along pristine sand with no one around is a vision hard to let go of, and there are many beaches in Asia that allow this vision to come to light, and interestingly, there is no off season if you want a trip to Asia, there is a getaway spot for you in Thailand and Malaysia from November to February and there is no better time to visit Bali than June to August. The water is still unpolluted, clear blue, the landscape still beautiful and lush, but the chance of having a beach to yourself, or at least with much fewer interlopers on your personal paradise is much higher. This does not mean that there isn't many hotels in Asia that are located near the amazing beaches.
To top things off, beaches in Asia give a sensation of a tropical island; complete with brightly colored parrots flying through the air, and monkeys chattering in the trees and swinging from branch to branch. Diving into the clear blue water of a lagoon is a depiction seen often in movies; the reality of actually doing so is attainable here, letting you live out fantasies uninterrupted by hoards of people milling about. Further fuelling this dream is the possibility of staying in a bungalow close to the water's edge, or walking through lush vegetation to reach your destination.
The other side of the picture offers an array of shopping and dining experiences unique to the area. An added plus to Asian beaches is the opportunity to immerse in a different culture. Learning the history of the area with local tour guides, or exploring by yourself and letting the ebb and flow of the lives around you soak into your being. The serenity found cannot be beat, even by other areas sensationalized for their tranquillity.
WASHINGTON, July 24 (Xinhua) -- An experimental HIV vaccine regimen was well-tolerated and generated immune responses against HIV in an early-stage clinical trial called APPROACH that involved nearly 400 healthy adults, the U.S. National Institutes of Health (NIH) said Monday.
The APPROACH findings will help decide whether to move forward with a larger trial in southern Africa to evaluate vaccine safety and efficacy among women at risk of acquiring HIV, the U.S. health agency said in a statement.
The experimental vaccine regimens evaluated in APPROACH are based on "mosaic" vaccines designed to induce immunological responses against a wide variety of HIV subtypes responsible for HIV infections globally.
The trial involved nearly 400 volunteers in the United States, Rwanda, Uganda, South Africa and Thailand who were randomly assigned to receive one of seven experimental vaccine regimens or a placebo.
While different mosaic vaccine regimens were well-tolerated and capable of generating anti-HIV immune responses in healthy, HIV-negative adults, one regimen that was most protective in pre-clinical studies in animals elicited the greatest immune responses in the study participants.
The NIH said the findings from APPROACH, as well as from animal studies, support further evaluation of this regimen in a clinical trial to assess its safety and efficacy.
"Plans for such a clinical trial to be conducted in southern Africa are in development, with projected enrollment of 2,600 healthy, HIV-negative women," it said.
"Should the larger trial move forward, it is expected to begin enrollment in late 2017 or early 2018."
In APPROACH, study participants received four vaccinations over 48 weeks: two doses of an initial, or "prime," vaccine, followed by two doses of a booster vaccine.
The experimental regimens all incorporated the same vaccine components in the prime vaccination, known as Ad26.Mos.HIV, while the booster vaccination included various combinations of the Ad26.Mos.HIV components or a different mosaic component, called MVA-Mosaic, andor two different doses of the soluble protein Clade C gp140 containing an aluminum adjuvant to boost immune response.
In pre-clinical monkey studies, the most effective prime-boost regimen reduced the risk of infection per exposure to an HIV-like virus called simian human immunodeficiency virus by 94 percent and resulted in 66 percent complete protection after six exposures.
The National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH, funded pre-clinical development of these mosaic vaccines, while the manufacture and clinical development are led by the Janssen Pharmaceutical Companies of Johnson & Johnson.
"A safe and effective HIV vaccine would be a powerful tool to reduce new HIV infections worldwide and help bring about a durable end to the HIVAIDS pandemic," NIAID Director Anthony Fauci said in the NIH statement.
"By exploring multiple promising avenues of vaccine development research, we expand our opportunities to achieve these goals," Fauci added.
People buy special candies and sweets for the Prophet Muhammad's birthday celebration at a market in Cairo, Egypt, on Nov. 22, 2017. In Egypt, the birthday of Islam's Prophet Muhammad falls this year on Dec. 1. As the anniversary gets closer, shops and streets across Egypt get crowded with distinctive swee. Cheap Indianapolis Colts Jerseys Cheap Kansas City Chiefs Jerseys Cheap Arizona Cardinals Jerseys Cheap Denver Broncos Jerseys Cheap Buffalo Bills Jerseys Cheap Cincinnati Bengals Jerseys Wholesale Bears Jerseys Wholesale Vikings Jerseys Wholesale Titans Jerseys Wholesale Pittsburgh Steelers Jerseys |
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